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For these people should prioritise taking doses in the evening according to medical reviews published in the Journal of Clinical Lipidology. Taking them at this time they found results in lower cholesterol compared to morning doses. Statin Therapy In The Older Patient When To Use It What To Watch For And When To Stop Population Health Learning Network Common medications usually act over a 24-hour period and are best taken in the early evening. Best time to take statins . Best Time to Take Statins. Although most statins may be taken without regard to meals immediate-release IR lovastatin should be taken with the evening meal because of increased bioavailability. This is especially likely if your blood sugar is already high. Statins have potentially serious side effects and there are instances in which they should not be taken. When to Take Antihistamines. They are Lipitor atorvastatin Crestor Rosuvastatin Pravachol. The studies that support morning dosing of simvas